Duke Infective Endocarditis Criteria 3.0 for the Clinician: Defining What Is Possible (2024)

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Volume 78 Issue 4 15 April 2024

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Henry F Chambers

Division of HIV, Infectious Diseases, and Global Medicine, University of California

San Francisco, California

USA

Correspondence: H. F. Chambers, Department of Medicine, Division of HIV, Infectious Diseases, and Global Medicine, Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue, San Francisco, CA 94110 (henry.chambers@ucsf.edu).

https://orcid.org/0000-0001-5317-4491

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ShanShan Zhang

Biostatistics Center, Milken Institute School of Public Health, George Washington University

Washington D.C.

USA

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Scott Evans

Biostatistics Center, Milken Institute School of Public Health, George Washington University

Washington D.C.

USA

https://orcid.org/0000-0003-3186-172X

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Clinical Infectious Diseases, Volume 78, Issue 4, 15 April 2024, Pages 964–967, https://doi.org/10.1093/cid/ciae037

Published:

08 February 2024

Article history

Received:

15 November 2023

Extract

(See the Major Articles by van der Vaart et al. on pages 922–9; Moisset et al. on pages 930–6; Goehringer et al. on pages 937–48; Papadimitriou-Olivgeris et al. on pages 949–55; Lindberg et al. on pages 956–63.)

The Duke criteria for the diagnosis of infective endocarditis, originally proposed in 1994 [1] and modified in 2000 [2], classifies diagnosis into 1 of 3 mutually exclusive categories: definite, possible, and rejected endocarditis. The criteria were developed as a research tool to identify patients with a high probability of infective endocarditis (ie, “definite” endocarditis) for inclusion in epidemiologic studies and treatment trials. These criteria have become the standard by which clinicians decide which patients with suspected endocarditis to treat for this infection.

The 2023 Duke–International Society for Cardiovascular Infectious Diseases Criteria for Infective Endocarditis (2023 criteria) [3] is an updated version of the 2000 modified Duke criteria (2000 criteria). It incorporates advances in microbiology and imaging and changes in epidemiology that have occurred over the last 20 years with the goal of improving sensitivity and specificity. Five articles reporting results of validation studies [4–8] were reviewed to assess whether this is indeed the case.

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